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Journal of Psychopharmacology
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0269881106072386v1
21/6/645    most recent
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Article

Benzodiazepines - a necessary evil? A survey of prescribing at a specialist UK psychiatric hospital

Camilla Haw* Jean Stubbs

St. Andrew's Hospital, Northampton, UK.

* To whom correspondence should be addressed.


  Abstract

Guidelines on the prescription of benzodiazepines recommend their use be limited to the short-term relief of severe anxiety or insomnia. However, clinical experience suggests that in psychiatry these drugs may be being prescribed more widely. The aim of this survey was to investigate benzodiazepine prescribing in a specialist UK psychiatric hospital using a structured interview with consultant psychiatrists. Prescribers were also asked their views on the UK CSM guidance on benzodiazepines (1988). Of 412 inpatients, 77 (18.7%) were receiving 90 benzodiazepine prescriptions for psychiatric indications. Most prescriptions were for anxiety (45/90; 50.0%), aggression (23/90; 25.6%) and agitation (13/90; 14.4%). Use was commonest for acquired brain injury, schizophrenia and personality disorders. Much usage was chronic (only 4/90 (4.4%) prescriptions had been initiated within the previous 4 weeks) and off-label (85/90; 94.4%). Prescribers were concerned about the addictive nature of benzodiazepines for these patients and to a lesser extent about their abuse potential. Most consultants believed the UK CSM guidance was too restrictive in relation to their clinical practice and needed modification to encompass new indications, for example rapid tranquillization, and specialist prescribing. In psychiatry benzodiazepines are quite frequently used in the management of a number of groups of difficult to treat patients. Although largely not evidence based, some psychiatrists report a favourable risk-benefit ratio for benzodiazepines in the treatment of certain patients.

Key Words: benzodiazepines, psychiatry, aggression, anxiety, schizophrenia

First published on November 8, 2006, doi:10.1177/0269881106072386

Journal of Psychopharmacology 2007;21:645.

A more recent version of this article appeared on August 1, 2007

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