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Journal of Psychopharmacology
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0269881106059696v1
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*Compound via MeSH
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*Cardiomyopathy
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*LITHIUM COMPOUNDS
*LITHIUM, ELEMENTAL
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Article

Cardiomyopathy after long-term treatment with lithium - more than a coincidence?

W. Aichhorn1*, R. Huber2, C. Stuppaeck3, A.B. Whitworth3

1 Department of Psychiatry, Innsbruck Medical University, Innsbruck, Austria
2 Department of Internal Medicine, PMU Salzburg, Salzburg, Austria
3 Department of Psychiatry 1, PMU Salzburg, Salzburg, Austria

* To whom correspondence should be addressed.


  Abstract
We describe a patient suffering from dilative cardiomyopathy after 16 years of treatment with lithium carbonate. The literature concerning lithium and cardiac adverse reactions is briefly reviewed. There is good evidence for acute cardiac reactions, especially cardiac arrhythmia but a rather speculative association with long-term reactions such as cardiomyopathy. Nevertheless clinicians should be aware of this rare but life threatening conjunction of cardiac disease and lithium treatment.

Key Words: lithium, cardiomyopathy, bipolar disorder, adverse drug reactions

First published on January 9, 2006, doi:10.1177/0269881106059696

Journal of Psychopharmacology 2006;20:589.

A more recent version of this article appeared on July 1, 2006

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