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Journal of Psychopharmacology
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Letter

Recurrent priapism during treatment with clozapine, quetiapine and haloperidol

Hygiea Casiano

Department of Psychiatry, University of Manitoba, Manitoba, Canada, Hygiea_casiano{at}hotmail.com

Daniel Globerman

Department of Psychiatry, University of Manitoba, Manitoba, Canada

Murray W. Enns

Department of Psychiatry, University of Manitoba, Manitoba, Canada

The following is a letter to the editor that represents a case of recurrent priapism. The patient received clozapine, quetiapine and haloperidol and had the adverse reaction of priapism, one episode of which required surgical intervention. This case highlights the need for physicians to be aware of the potential for this serious adverse effect and to be especially mindful to carefully monitor those patients who have already had one episode of priapism as they may be at risk for recurrence.

Key Words: priapism • antipsychotics • clozapine • quetiapine • haloperiodol • adverse reaction • side effects

References

  • Cherian J., Rao A.R., Thwaini A., Kapasi F., Shergill I.S., Samman R. (2006) Medical and surgical management of priapism. Postgraduate Medicine 82: 89—94[Abstract/Free Full Text]
  • Compton M., Miller A.H. (2001) Priapism associated with conventional and atypical antipsychotic medications: A review. Journal of Clinical Psychiatry 62: 362—366
  • du Toit R.M., Millson R.C., Heaton J.P., Adams M.A. (2004) Priapism. Canadian Journal of Psychiatry 49: 868—869[Medline] [Order article via Infotrieve]
  • Davol P., Rukstalis D. (2005) Priapism associated with routine use of quetiapine: Case report and review of the literature. Urology 66: e13—e14[Web of Science]
  • Reeves R.R., Mack J.E. (2002) Priapism associated with two atypical antipsychotic agents. Pharmacotherapy 22: 1070—1073[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Richelson E. (1999) Receptor pharmacology of neuroleptics: relation to clinical effects. Journal of Clinical Psychiatry 60 (Suppl 10): 5—14
  • Negin B., Murphy T.K. (2005) Priapism associated with oxcarbazepine, aripiprazole, and lithium. Journal of American Academy of Child and Adolescent Psychiatry 44: 1223—1224[Medline] [Order article via Infotrieve]
  • Jagadheesan K., Thakur A., Akhtar S. (2004) Irreversible priapism during olanzapine and lithium therapy. Australian and New Zealand Journal of Psychiatry 38: 381[Web of Science][Medline] [Order article via Infotrieve]
  • Owley T., Leventhal B., Cook E.H. (2001) Risperidone-induced prolonged erections following the addition of lithium. Journal of Child and Adolescent Psychopharmacology 11: 441—442[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Mendelson W.B., Franko T. (1994) Priapism with sertraline and lithium. Journal of Clinical Psychopharmacology 14: 434—435[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Sadeghi-Nejad H., Dogra V., Seftel A.D., Mohamed M.A. (2004) Priapism. Radiology Clinics of North America 42: 427—443

This version was published on November 1, 2007

Journal of Psychopharmacology, Vol. 21, No. 8, 898-899 (2007)
DOI: 10.1177/0269881107077372


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This Article
Right arrow Abstract Freely available
Right arrow Free Full Text (Free PDF) Free
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Casiano, H.
Right arrow Articles by Enns, M. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Casiano, H.
Right arrow Articles by Enns, M. W.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*CLOZAPINE
*HALOPERIDOL
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

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