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Increased libido associated with quetiapine

St. George’s Hospital, Morpeth, Northumberland, UK

R. Hamish McAllister Williams

School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Newcastle upon Tyne, UK

Stuart Watson

School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Newcastle upon Tyne, UK. Mental Health Unit, Leazes Wing, RVI, Newcastle, UK, stuart.watson{at}ncl.ac.uk

We report sexual symptoms in a 44 year old man with schizophrenia who was receiving treatment with the atypical antipsychotic quetiapine. The symptoms consisted of an increased drive to masturbate and spontaneous ejaculations at night time. We discuss the potential neuro-chemical mechanisms for this and argue that quetiapine’s unique pharmacological profile may have contributed to the development of his symptoms.

Key Words: quetiapine • libido • neurotransmitters • serotonin • adrenoceptor • prolactin • dopamine

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Journal of Psychopharmacology, Vol. 20, No. 1, 125-127 (2006)
DOI: 10.1177/0269881106059732


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Menon, A. Articles by Watson, S. Search for Related Content PubMed PubMed Citation Articles by Menon, A. Articles by Watson, S. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Medline Plus Health Information Schizophrenia Social Bookmarking                         What's this?