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Journal of Psychopharmacology
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Fluparoxan in male erectile disorder: a case report

O. Le Bon

Consultants in Neuropsychiatry, Universite Libre de Bruxelles, Brugmann University Hospital, Service de Psychiatrie et de Psychologie medicale (Professor I. Pelc), 4, Pl. Van Gehuchten, 1020 Brussels, Belgium

K. Lion

Consultants in Neuropsychiatry, Universite Libre de Bruxelles, Brugmann University Hospital, Service de Psychiatrie et de Psychologie medicale (Professor I. Pelc), 4, Pl. Van Gehuchten, 1020 Brussels, Belgium

P. Verbanck

Consultants in Neuropsychiatry, Universite Libre de Bruxelles, Brugmann University Hospital, Service de Psychiatrie et de Psychologie medicale (Professor I. Pelc), 4, Pl. Van Gehuchten, 1020 Brussels, Belgium

C. Kornreich

Consultants in Neuropsychiatry, Universite Libre de Bruxelles, Brugmann University Hospital, Service de Psychiatrie et de Psychologie medicale (Professor I. Pelc), 4, Pl. Van Gehuchten, 1020 Brussels, Belgium

During a protocol study for the efficacy of fluparoxan (a noradrenergic {alpha}2-antagonist) in depression, a positive effect on male erectile impotence has been observed in one case, with no important secondary effects. This result confirms the involvement of {alpha}2-antagonists in the handling of male impotence. The action on the erectile disorder appeared slightly before the antidepressive effect (2-3 weeks) and lasted for 6 weeks after the discontinuation of treatment, suggesting that the effects on impotence were not a mere reflection of the antidepressive action.

Key Words: impotence • adrenergic {alpha}2-receptor blockaders • yohimbine • fluparoxan • case report

Journal of Psychopharmacology, Vol. 9, No. 1, 67-68 (1995)
DOI: 10.1177/026988119500900111
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