This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Reveley, M.A. Articles by Andrews, H. Search for Related Content PubMed Articles by Reveley, M.A. Articles by Andrews, H. Social Bookmarking                         What's this?

Improvement of abnormal saccadic eye movements in Huntington's disease by sulpiride: a case study

Department of Psychiatry, Faculty of Medicine, University of Leicester, Leicester LE2 7LX, UK

S.M. Dursun

Department of Psychiatry, Faculty of Medicine, University of Leicester, Leicester LE2 7LX, UK

H. Andrews

Department of Psychiatry, Faculty of Medicine, University of Leicester, Leicester LE2 7LX, UK

Sulpiride treatment improved both the abnormal asymmetric saccadic eye movements (SEM) and the abnormal involuntary movements (AIMs) in a patient with Huntington's disease (HD). However, sulpiride corrected the abnormalities of SEM in the right, but not the left, hemi-field and the degeneration of the left striatal tissue was greater as visualised by the magnetic resonance imaging (MRI) scan.

Key Words: saccades • Huntington's disease • sulpiride • actometer • case report

Journal of Psychopharmacology, Vol. 8, No. 4, 262-265 (1994)
DOI: 10.1177/026988119400800411


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				S. M. Dursun, J. G. Burke, and M. A. Reveley Antisaccade eye movement abnormalities in Tourette syndrome: evidence for cortico-striatal network dysfunction? J Psychopharmacol, January 1, 2000; 14(1): 37 - 39. [Abstract] [PDF]

				S. M. Dursun, N. Wright, and M. A. Reveley Effects of amphetamine on saccadic eye movements in man: possible relevance to schizophrenia? J Psychopharmacol, May 1, 1999; 13(3): 245 - 247. [Abstract] [PDF]

				M.A. Reveley, S.M. Dursun, and H. Andrews A comparative trial use of sulpiride and risperidone in Huntington's disease: a pilot study J Psychopharmacol, January 1, 1996; 10(2): 162 - 165. [Abstract] [PDF]