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Is there a distinct subtype of major depression in the elderly?

Consultant Psychiatrist for the Elderly, York House, Manchester Royal Infirmary, Oxford Road, Manchester M13 9BX, UK

Evidence for and against the notion of a specific subtype of depressive illness in the elderly is reviewed. There is little to support a distinction based on clinical features, neurobiological markers, treatment response or prognosis, but subtle organic cerebral change may predispose to late-onset depression in a significant minority of cases.

Key Words: depression • ageing • elderly • symptoms • prognosis • organic • aetiology

Journal of Psychopharmacology, Vol. 8, No. 3, 177-184 (1994)
DOI: 10.1177/026988119400800307


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