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Olanzapine treatment in Jarisch-Herxheimer reaction due to neurosyphilis with dementia: a case report

Department of Psychiatry, GATA Haydarpasha Training Hospital, Istanbul, Turkey, aates1971{at}yahoo.com

A. Algul

Department of Psychiatry, GATA Haydarpasha Training Hospital, Istanbul, Turkey

O. Gecici

Department of Psychiatry, Medicine School, Afyon Kocatepe University, Afyon, Turkey

UB Semiz

Department of Psychiatry, GATA Haydarpasha Training Hospital, Istanbul, Turkey

O. Yilmaz

Department of Psychiatry, GATA Haydarpasha Training Hospital, Istanbul, Turkey

M. Gulsun

Department of Psychiatry, Isparta Military Hospital, Isparta, Turkey

We discussed a neurosyphilis case who had a risky sexual intercourse history nearly 10 years ago. After the neurosyphilis diagnosis, the patient has clinical symptoms of a demential case starting as a typical manic episode and Jarisch-Herxheimer reaction because of intravenous penicillin treatment that has improved with olanzapine treatment.

Key Words: dementia • Jarisch-Herxheimer reaction • neurosyphilis • olanzapine

This version was published on November 1, 2009

Journal of Psychopharmacology, Vol. 23, No. 8, 999-1000 (2009)
DOI: 10.1177/0269881108093585


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