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Journal of Psychopharmacology
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0269881108093843v1
23/8/993    most recent
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The potential relationship between QTc interval prolongation and ziprasidone treatment: three cases

SS Eker

Psychiatry Department, Uludag University Medical Faculty, Bursa, Turkey, saygineker{at}yahoo.com

A. Sarandol

Psychiatry Department, Uludag University Medical Faculty, Bursa, Turkey

C. Akkaya

Psychiatry Department, Uludag University Medical Faculty, Bursa, Turkey

EY Sivrioglu

Psychiatry Department, Uludag University Medical Faculty, Bursa, Turkey

S. Kirli

4 Psychiatry Department, Uludag University Medical Faculty, Bursa, Turkey

QTc interval prolongation may appear as a consequence of both typical and atypical antipsychotic treatments. Ziprasidone, which is effective in treating schizophrenia, is associated with QTc prolongation. Although the prolongation of QTc with ziprasidone treatment is often pronounced, there is a scarce number of cases reported about the relationship between ziprasidone and QTc prolongation. Of the three cases presented in this case series, two cases showed values exceeding 0.50 s with ziprasidone treatment.

Key Words: antipsychotic • QTc prolongation • ziprasidone

This version was published on November 1, 2009

Journal of Psychopharmacology, Vol. 23, No. 8, 993-996 (2009)
DOI: 10.1177/0269881108093843
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