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Journal of Psychopharmacology
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0269881106060660v1
20/5/708    most recent
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Antidepressants and dizziness

Renato T. Ramos

University of São Paulo Medical School, São Paulo, Brazil

Despite several evidences supporting a close relationship between dizziness and anxiety symptoms, the role of antidepressants in the treatment of such conditions remains poorly explored. The high prevalence of dizziness during serotonin reuptake inhibitors discontinuation syndrome and the few reports suggesting efficacy of antidepressants in treating some vestibular disorders justify a careful investigation. Neurophysiologic studies suggest possible focus of investigation on mechanisms of drug action. Psychophysiologic studies also suggest a possible role of antidepressant drugs in improving balance control and cognitive functioning. Controlled studies involving antidepressants with selective action in different neurotransmitters systems are necessary to elucidate the complex pathophysiologic mechanisms involving emotional and balance control. For future researches, special attention must be paid to the methodology of balance evaluation and the interaction between posture control and cognitive functioning.

Key Words: dizziness • antidepressants • balance control • vestibular testing • anxiety

This version was published on September 1, 2006

Journal of Psychopharmacology, Vol. 20, No. 5, 708-713 (2006)
DOI: 10.1177/0269881106060660
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 Scand J Public HealthHome page
A.-L. Tamber and D. Bruusgaard
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Scand J Public Health, August 1, 2009; 37(6): 613 - 620.
[Abstract] [PDF]


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