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Journal of Psychopharmacology
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A case of Aripiprazole and extra pyramidal side effects

Alberto Salmoiraghi

Department of Psychiatry, Royal Liverpool University Hospital, Liverpool, UK.

Mahesh Odiyoor

Halton General Hospital, Runcorn, UK.

This is a case report of a 56-year-old lady who was admitted to a psychiatric ward because she was showing a plethora of positive and negative symptoms of schizophrenia. She has a positive history of mental illness; her mother had a diagnosis of schizophrenia. The patient did not have any medical history of relevance and was not taking any medication. She was commenced on Aripiprazole and after 5 weeks developed disabling extra-pyramidal side effects. On discontinuation of Aripiprazole, the side effects subsided and disappeared quickly. According to the authors’ knowledge, this is the first case of a patient developing extra-pyramidal side effects following treatment with Aripiprazole, not previously exposed to other antipsychotic, and with no co-morbid medical conditions. The authors suggest titrating Aripiprazole slowly.

Key Words: Aripiprazole • atypical antipsychotics extra-pyramidal side effects • schizophrenia • parkinsonism

This version was published on July 1, 2006

Journal of Psychopharmacology, Vol. 20, No. 4, 592-593 (2006)
DOI: 10.1177/0269881106060194
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