This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (3) Citing Articles via Google Scholar Google Scholar Articles by Hallak, J. E. C. Articles by Deakin, J. F. W. Search for Related Content PubMed PubMed Citation Articles by Hallak, J. E. C. Articles by Deakin, J. F. W. Social Bookmarking                   What's this?

Olanzapine for Recurrent Aggression in a Patient with Temporal Lobe Epilepsy who had Temporal Lobectomy

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine University of São Paulo, Ribeirão Preto, São Paulo, Brazil, School of Psychiatry and Behavioural Sciences, Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK, jaime.hallak{at}man.ac.uk

Serdar M. Dursun

School of Psychiatry and Behavioural Sciences, Neuroscience and Psychiatry Unit, University of Manchester, Manchester UK

Ricardo Guarnieri

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

Edna Almeida

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

Karinne Rezeck

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

José A. S. Crippa

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil, Department of Psychological Medicine, Institute de Psychiatry, University of London, London, UK

Américo C. Sakamoto

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

Antonio W. Zuardi

Department of Neuropsychiatry and Medical Psychology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

John F. W. Deakin

School of Psychiatry and Behavioural Sciences, Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK.

We report the case of a patient with epilepsy who had interictal severe affective aggression, and whose epilepsy significantly improved (but not aggression) after successful temporal lobectomy. Olanzapine significantly improved these aggressive episodes refractory to neurosurgery and previous pharmacological treatments including antipsychotics, anticonvulsants/mood stabilizers and benzodiazepines.

Key Words: aggression • epilepsy • olanzapine • temporal lobectomy

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				K. Tritt, C. Nickel, C. Lahmann, P. K. Leiberich, W. K. Rother, T. H. Loew, and M. K. Nickel Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study J Psychopharmacol, May 1, 2005; 19(3): 287 - 291. [Abstract] [PDF]