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Journal of Psychopharmacology
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A case of depersonalization–derealization syndrome during treatment with quetiapine

Jaydip Sarkar

St Tydfil's Hospital, Merthyr Tydfil, Wales, UK

Neil Jones

St Tydfil's Hospital Merthyr Tydfil CF47 0SJ Wales, UK

Gary Sullivan

St Tydfil's Hospital, Merthyr Tydfil, Wales, UK

A case is reported of a 65-year-old male patient with schizophrenia who developed depersonalization–derealization syndrome following treatment with quetiapine, an atypical antipsychotic. The literature is reviewed for possible biological mechanisms that may account for this phenomenon.

Key Words: antipsychotic agents • depersonalization • depersonalization-derealization syndrome • derealization • quetiapine • schizophrenia

Journal of Psychopharmacology, Vol. 15, No. 3, 209-211 (2001)
DOI: 10.1177/026988110101500309
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