This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Barbenel, D. M. Articles by Bench, C. J. Search for Related Content PubMed PubMed Citation Articles by Barbenel, D. M. Articles by Bench, C. J. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Medline Plus Health Information Antidepressants Bipolar Disorder Hazardous Substances DB SERTRALINE TESTOSTERONE Social Bookmarking                         What's this?

Mania in a patient receiving testosterone replacement post-orchidectomy taking St John’s wort and sertraline

Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Charing Cross Hospital, London, UK

B. Yusufi

Department of Psychiatry, Charing Cross Hospital, London, UK

D. O’Shea

Department of Endocrinology, Charing Cross Hospital, London, UK

C. J. Bench

Department of Psychiatry, Charing Cross Hospital, London, UK

We describe the case of a patient who developed depression following bilateral orchidectomy for cryptorchidism. He was treated with a conventional selective serotonin reuptake inhibitor antidepressant, but continued to take St John’s wort (hypericum) against medical advice. He subsequently developed a manic episode. We discuss postulated modes of action of St John’s wort and the possible aetiological importance of testosterone replacement and abnormal gonadotrophin levels in this case.

Journal of Psychopharmacology, Vol. 14, No. 1, 84-86 (2000)
DOI: 10.1177/026988110001400113


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				J. Boullata Natural Health Product Interactions with Medication Nutr Clin Pract, February 1, 2005; 20(1): 33 - 51. [Abstract] [Full Text] [PDF]

				A. Sparreboom, M. C. Cox, M. R. Acharya, and W. D. Figg Herbal Remedies in the United States: Potential Adverse Interactions With Anticancer Agents J. Clin. Oncol., June 15, 2004; 22(12): 2489 - 2503. [Abstract] [Full Text] [PDF]

				S. Zhou, E. Chan, S.-Q. Pan, M. Huang, and E. J. D. Lee Pharmacokinetic Interactions of Drugs with St John's Wort J Psychopharmacol, June 1, 2004; 18(2): 262 - 276. [Abstract] [PDF]

				P. Hammerness, E. Basch, C. Ulbricht, E.-P. Barrette, I. Foppa, S. Basch, S. Bent, H. Boon, and E. Ernst St. John's Wort: A Systematic Review of Adverse Effects and Drug Interactions for the Consultation Psychiatrist Psychosomatics, August 1, 2003; 44(4): 271 - 282. [Abstract] [Full Text] [PDF]

				V. Novak-Grubic and R. Tavcar Autocastration and Schizophrenia Psychiatr Serv, April 1, 2002; 53 (4): 485 - 486. [Full Text] [PDF]