SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Journal of Psychopharmacology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by McCreadie, R.G.
Right arrow Articles by Paterson, J.R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by McCreadie, R.G.
Right arrow Articles by Paterson, J.R.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Plasma lipid peroxide and serum vitamin E levels in subjects taking antipsychotic drugs

R.G. McCreadie

Crichton Royal Hospital, Dumfries DG14TG

J. Halliday

Greencroft Medical Centre, Annan DG12 6GB

T. MacEwan

Crichton Royal Hospital, Dumfries DG14TG

D. Hinselwood

Department of Biochemistry, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP, UK

G. Campbell

Department of Biochemistry, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP, UK

J.R. Paterson

Department of Biochemistry, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP, UK

Fourteen non-schizophrenic subjects were identified in a group general practice as taking antipsychotic medication. They were matched with a control group on age, gender and smoking status. Blood samples were taken to measure plasma lipid peroxide, serum vitamin E and cholesterol and vitamin E:cholesterol ratios. The majority of subjects were taking thioridazine (mean daily dose 42 mg, range 20-100 mg). There were no statistically significant differences between subjects and controls in any of the laboratory measures. The results in this small study therefore do not support the hypothesis that a possible source of increased free radical activity in schizophrenic patients is antipsychotic medication.

Key Words: antipsychotic drugs • lipid peroxide • vitamin E

Journal of Psychopharmacology, Vol. 10, No. 4, 295-297 (1996)
DOI: 10.1177/026988119601000406
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




Advertisement